Fibroscan/Transient Elastography

  • – It uses US waves to measure hepatic stiffness non-invasively

                               Principle:

  • – Fibrosis leads to  stiffness of the tissue
  • – A shear wave will propagate faster through stiff material than through elastic material
  • – USG transducer emits low frequency (50 HZ) shear wave to go through a set ‘window’ of tissue measured
  • – This window of tissue is 1×4 cm   100 times the area of an average liver biopsy
  • – Fibroscan best performed to differentiate cirrhosis from absence of cirrhosis but less accurate to measure lesser degree of fibrosis
  • – Fibroscan is accurate for identifying advanced fibrosis in patients with
  •                          • Chronic HCV
  •                          • PBC
  •                          • Hemochromatosis
  •                          • NAFLD
  •                          • Recurrent chronic hepatitis after LT

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